Pulmonary Embolism Treatment
Systemic Thrombolysis

Pulmonary Embolism Treatment

Systemic Thrombolysis

 - Exclude contraindications.

 - Indications:

   - Massive PE (definite indication)

   - High-risk submassive PE (risk/benefit)

 - Std dose alteplase = 100mg IV over 2 hrs

 - Low dose 0.5 mg/kg (up to 50mg IV)

 - 2% risk of ICH and 6% risk of other major bleeding with tPA (PIETHO)

Catheter Directed Lysis

 - Useful in patients who are higher risk for thrombolysis. May be superior to anticoag alone-in intermediate risk PE.


 - May be useful in patients who fail above therapies, who have C/I to thrombolysis, or who require surgery for large RA thrombus

Nick Mark MD @nickmmark

#Pulmonary #Embolism #Treatment #AcutePE #Management #CriticalCare
Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
Medical jobs
view all


Related content