Chagas Disease - Acute, Chronic and Reactivation 



Acute Chagas

 - 95% asymptomatic

 - Chagoma (Romana's sign), nonspecific fever (can mimic mononucleosis, acute HIV, etc)

 - Severe forms: meningoencephalitis, myocarditis (CHF > arrhythmia)

Chronic Chagas

 - Indeterminate - No signs or symptoms

 - Determinate

    - Cardiomyopathy (arrhythmia > CHF)

    - GI (megaesophagus, megacolon) — limited to the Southern Cone

Reactivation Chagas

 - Transplant patients, HIV, chemo, etc

 - CNS (meningoencephalitis, brain abscess)

 - Acute myocarditis

 - Can have a rash (red plaques, papules, nodules, ulcers)



WuidQ: Washington University ID Questions @WuidQ



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