Anticonvulsants as Mood Stabilizers: Mechanism and ...
797
Description

Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect

Examples: Valproate, Carbamazepine, Lamotrigine

 • Mild anticholinergic effect -> Drowsiness dry mouth, blurred vision constipation

 • Allergic reaction -> Benign Rash

 • T-cell mediated cytotoxic reaction to drug antigens -> Potentially life threatening - Stevens-Johnson Syndrome

 • Abrupt discontinuation or decr intake -> Withdrawal seizure, relapse of bipolar disorder

 • Inhibition of dopaminergic activity -> Dose-dependent tremor, ataxia, asthenia

 • Neurologic effect - Sedation, dose-dependent tremor, dizziness, diplopia, ataxia, asthenia, headache

 • Systemic effect -> Nausea,  vomiting, diarrhea, hyponatremia, rash, pruritus, weight gain, alopecia (unusual), thrombocytopenia



#Anticonvulsants #MoodStabilizers #Mechanism #SideEffects #Pathophysiology #Psychiatry #Pharmacology
Contributed by

The Calgary Guide to Understanding Disease
@TheCalgaryGuide
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Medical jobs
view all

0 Comments

Related content