Major Depressive Disorder (MDD): Pathogenesis and Clinical ...
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings



Symptoms (included in DSM 5 criteria) - Present during same two week period and represent change from previous functioning:

 - Anhedonia (loss of interest/pleasure)

 - Anergia (fatigue)

 - Insomnia or hypersomnia

 - Feelings of worthlessness or excessive guilt

 - Poor cognition/concentration

 - Depressed Mood

 - Appetite or weight change (Incr or Decr)

 - Psychomotor agitation or retardation

 - Recurrent thoughts of death or suicide

Other Symptoms:

 - Loss of libido

 - Mood varies by time of day (diurnal variation)

 - Worse in winter (Seasonal Affective Disorder)

 - Onset in month after delivery (MDD with post partum onset)

 - Anxiety

 - Hallucinations (MDD with psychotic features)

 - Delusions (MDD with psychotic features)



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The Calgary Guide to Understanding Disease
@TheCalgaryGuide
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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