Hyperuricemia - Differential Diagnosis Algorithm
Primary ...
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Description

Hyperuricemia - Differential Diagnosis Algorithm

Primary - Over-production

     • Increased turnover of nucleotides

Primary - Under-excretion

     • Lower uric acid clearance

     • Starvation

Secondary - Over-production 

 - Lymphoproliferative Disorders

     • Acute Lymphoblastic Leukemia (ALL)

     • Acute Myeloid Leukemia (AML)

     • Chronic Myeloid Leukemia (CML)

 - Hemolytic Anemia

 - Others

     • Psoriasis

     • Chemotherapy

     • Drug-induced

     • High purine diet

Secondary - Under-excretion

 - Endocrine

     • Hyperparathyroidism

     • Diabetic acidosis

 - Renal

     • Chronic renal failure

     • Sarcoidosis

     • Hypercalcemia

 - Drug-Induced

     • Antiuricosuric drugs

     • ACE inhibitors

     • Cyclosporine

     • Diuretics

     • Organic acids

     • Ethambutol

     • Alcohol



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