Causes of Peripheral Weakness without Sensory Changes ...
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Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm

No Objective Weakness

 • Cardio-pulmonary disease

 • Anemia

 • Chronic Infection

 • Malignancy

 • Depression

 • Deconditioning

 • Arthritis

 • Fibromyalgia

 • Endocrine Disease

Motor Neuron and Motor Neuropathy - Atrophy, Fasciculations, Hyperreflexia

 • Lead toxicity

 • Progressive muscular atrophy

 • Hodgkin's lymphoma

 • Polio

 • Multifocal Motor Neuropathy

 • Spinal Muscular Atrophy 

Neuromuscular Junction - Fatigability, Variability, Oculomotor

 • Myasthenia Gravis

 • Lambert-Eaton Myasthenic Syndrome

 • Botulism

 • Congenital

Myopathy - Proximal muscle involvement, elevated CK

 • Polymyositis

 • Duchenne Muscular Dystrophy

 • Statin Toxicity

 • Dermatomyositis

 • Viral infection



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