Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm

Radiculopathy:

 • Disc

 • Spondylosis

 • Tumor

 • Infection

Mononeuropathy - Compression:

 • Carpal Tunnel

 • Ulnar

 • Peroneal

 • Radial

Mononeuropathy - Other:

 • Trauma

 • Tumor

 • Ischemia 

Polyneuropathy (Length Dependent):

 • Diabetes

 • Nutrition

 • Alcohol

 • Toxins

 • Paraproteinemic

 • Inherited

 • Inflammation

Mononeuritis Multiplex:

 • Vasculitis

 • Diabetes 

Plexopathy:

 • Brachial neuritis

 • Diabetes

 • Tumor

Poly-Radiculopathy:

 • Spondylysis

 • Chronic Inflammatory Demyelinating Polyneuropathy

 • Neoplasm

 • Infection



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