Intern Pocket Cards - Inpatient Anti-Emetics Guide

Serotonin antagonists:

 • Ondansetron (Zofran), Granisetron (Kytril, Sancuso) - Headache, constipation, drowsiness, diarrhea

Dopamine antagonists (DA):

 • Metoclopramide (Reglan) -Drowsiness, EPS, do not use if increased GI motility

 • Olanzapine (Zyprexa) - EPS, hyperglycemia

 • Prochlorperazine (Compazine) - EPS, NMS

 • Haloperidol (Haldol) - EPS, constipation, dry mouth, blurred vision, somnolence

 • Chlorpromazine (Thorazine) - EPS, dry mouth

Histamine antagonists:

 • Diphenhydramine (Benadryl) - Dizziness, drowsiness, paradoxical excitation

ACh antagonists

 • Scopolamine - Bradycardia, flushing, thirst, xerostomia, urinary retention

DA/Histamine/ACh antagonist:

 • Promethazine (Phenergan) - EPS, NMS, drowsiness, sedation, leukopenia, thrombocytopenia

Neurokinin-1 receptor antagonists

 • Aprepitant (Emend) - Hiccups, bradycardia, neutropenia

 • Fosaprepitant (Ivemend) - Angioedema, bradycardia, neutropenia

Centrally acting:

 • Dexamethasone - Leukocytosis, mood changes, adrenal suppression, hyperglycemia

 • Trimethobenzamide (Tigan) - EPS, disorientation, seizure

 • THC, dronabinol - Hyperemesis, tachycardia, nystagmus, ataxia

 • Lorazepam (Ativan) - Respiratory depression



Dr. Satya Patel @SatyaPatelMD

Full Inpatient Pocket Cards Collection: https://bit.ly/pocketcardset



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