Effect of Selected Diseases on Complement Levels - C3, C4

 • SLE C3 ↓ C4 ↓↓

 • MCGN type 1 C3 ↓ C4 ↓↓

 • Cryo C3 ↓ C4 ↓↓

 • Hereditary angiooedema C3 C4 ↓↓

 • C3GN C3 ↓ C4 →

 • Infection eg SBE C3 ↓ C4 ↓ or →

 • PIGN C3 ↓ C4 →

 • Atheroemboli C3 ↓ C4 →

 • HUS C3 ↓ C4 →

 • Severe sepsis C3 ↓ C4 ↓ or →

 • Malnutrition C3 ↓ C4 →

 • Hepatic failure C3 ↓ C4 ↓



- Dr. John Booth @ThePeanutKidney



#Complement #Levels #C3 #C4 #differential #diagnosis #c4 #c3