Staphylococcus-associated GlomeruloNephritis - Diagnosis ...
382
Description

Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary

CLINICAL

 • Nephritic syndrome (Casts)

 • Marked proteinuria (may be nephrotic range)

 • Often severe renal impairment

 • 15% macroscopic haematuria

 • Leukocyturia

 • Vasculitic rash not uncommon

DIAGNOSIS

 • 80% ↓ C3 or CH50

 • ± ↓ C4

 • Microbial cultures

 • No serologic tests available

 • Renal biopsy

HISTOPATHOLOGY

 • Spectrum of abnormalities

 • Endocapillary exudative GN

 • C3/lgG or IgA (esp DM)

 • "starry sky"

 • Sub-epithelial humps

 • Sub-endothelial deposits common

TREATMENT

 • Supportive care

 • Antibiotics / source control

     - Pivotal in management

     - Surgery if needed

 • No role for IS

 • Resolution may take months

Follow-up:

 • CKD not uncommon

 • Unmasked C3GN rare



Dr. John Booth @ThePeanutKidney



#Staphylococcus #associated #GlomeruloNephritis #nephrology #diagnosis #management #GN
Contributed by

Dr. Gerald Diaz
@GeraldMD
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG:  https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
Medical jobs
view all

0 Comments

Related content