Metabolic Acidosis with Anion Gap - KILU Mnemonic
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Description

Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis

 • DKA

     - With normal glucose, ask if on SGLT2 inhibitor.

     - Eugylcyemic ketoacidosis in SGLT2 inhibitors and SGLT2 deficiency mutation

 • Alcohol ketoacidosis

     - 10% have -ve urine ketones (their ketone is B-hydroxy butyrate)

 • Starvation

I - Ingestions: ethylene glycol methanol (for those, check osm gap, & alcohol level salicylates (+ resp alkalosis}, APAP (rare in lit), iron (pediatric), paraldehyde

L - Lactate. 

 • Type A = tissue hypoxia (e.g. shock, dying gut/limb). 

 • Type B = lymphoma or leukemia or drug that results in lactate build-up, Beri-Beri, NRTl's, linezolid

U - Uremia. The anion is phosphate typically.



#KILU #Mnemonic #AnionGap #Metabolic #Acidosis #diagnosis #differential 
Contributed by

Dr. Ravi Singh K
@rav7ks
Academic Hospitalist and APD @SinaiBmoreIMRes, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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