Adrenoceptor Actions

α1

 • Vascular smooth muscle - Contraction

 • Genitourinary smooth muscle - Contraction

 • Intestinal smooth muscle - Relaxation

 • Heart - ↑ Inotropy and excitability

 • Liver - Gycogenolysis and gluconeogenesis

α2

 • Pancreatic ß-cells - ↓ Insulin secretion

 • Platelets - Aggregation

 • Nerve - ↓ Norepinephrine release

 • Vascular smooth muscle - Contraction

ß1

 • Heart - ↑ Chronotropy and inotropy

 • Heart - ↑ AV node conduction velocity

 • Renal juxtaglomerular cells - ↑ Renin secretion

ß2

 • Smooth muscle - Relaxation

 • Liver - Glycogenolysis and gluconeogenesis

 • Skeletal muscle - Glycogenolysis and K+ uptake

ß3

 • Adipose - Lipolysis



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