Pulmonary Hypertension Groups - WHO Classification
Group I - Vascular remodeling of pulmonary arteries
• Idiopathic, HIV, connective tissue disorders
Group II - Left-sided heart disease causing back up of blood flow
• Left heart failure, aortic valve disease, mitral valve disease
Group III - Chronic lung disease causing hypoxemia
• COPD, ILD, sleep apnea
Group IV - CTEPH
• Pulmonary Embolism
Group V - Unclear and multifactorial
• Sarcoidosis, chronic hemolytic anemia, thyroid disorders, sickle cell anemia, splenectomy, mediastinal tumors, chronic renal failure on hemodialysis
WHO PH Functional Classification
I - No limitation of usual physical activity
II - No issues at rest, but normal activity worsens dyspnea, fatigue, or chest pain.
III - No issues at rest, but normal activity is markedly limited by dyspnea, fatigue, chest pain, or pre-syncope.
IV - Unable to perform activity at rest. Symptoms of right ventricular failure might be present at rest.
- Dr. Rishi Kumar @rishikumarmd
#Pulmonary #Hypertension #PHTN #Groups #WHO #Classification #diagnosis