Cutaneous Manifestations of Monoclonal Gammopathy

 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic spicules

 • Intravascular lg deposits: Type I cryoglobulinemia

 • Autoantibody activity: Type II cryoglobulinemia, Cold agglutinin disease, Xanthomatosis

 • Cytokine secretion: POEMS syndrome, Syndrome Schnitzler

 • Unknown mechanism: Scleromyxoedema, Acquired cutis laxa, TEMPI syndrome, Pyoderma gangrenosum



By Dr. Nader Yatim @NaderYatim 



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