EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus

Clinical Domains:

 • Constitutional domain: Fever

 • Cutaneous domain: Non-scarring alopecia, Oral ulcers, Subacute cutaneous or discoid lupus, Acute cutaneous lupus

 • Arthritis domain: Synovitis or tenderness in at least 2 joints

 • Neurologic domain: Delirium, Psychosis, Seizure

 • Serositis domain: Pleural or pericardial effusion, Acute pericarditis

 • Hematologic domain: Leukopenia, Thrombocytopenia, Autoimmune hemolysis

 • Renal domain: Proteinuria > 0.5 g/24 hr, Class II or V lupus nephritis, Class Ill or IV lupus nephritis

Immunologic domains:

 • Antiphospholipid antibody domain: Anticardiolipin IgG > 40 GPL or anti-ß2GPI IgG > 40 units or lupus anticoagulant

 • Complement proteins domain: Low C3 or low C4, Low C3 and low C4

 • Highly specific antibodies domain: Anti-dsDNA antibody, Anti-Sm antibody



Dr. Laurent ARNAUD @Lupusreference



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