Hyponatremia Diagnosis Algorithm

UOsm ≥ POsm - Vasopressin-Dependent

 • UNa < 20 mEq/L - Appropriate (↓ EABV) - Consider: Hypovolemia, Heart failure, Cirrhosis

 • UNa > 30mEq/L - Inappropriate - Consider: SIADH, Cortisol deficiency

UOsm < POsm - Vasopressin-independent - Consider: Primary polydipsia, Low solute intake, Renal insufficiency



by Helbert Rondon, MD @NephroMD



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