Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs, NSAIDs, calcineurin inhibitors (e.g. cyclosporine, tacrolimus)
Intrarenal:
 • ATN: Aminoglycosides, cisplatin, tenofovir
 • AIN: Beta-lactams, vancomycin, sulfamethoxazole-trimethoprim (Bactrim), NSAIDs
 • Crystal nephropathy: Acyclovir, ganciclovir, ciprofloxacin, sulfamethoxazole, methotrexate
Postrenal -↓ bladder sensation, impaired detrusor contraction, and/or ↑ urinary sphincter tone:
 • Opiates
 • Sympathomimetics (e.g. nasal decongestants)
 • Any drug with anticholinergic effects (e.g. antihistamines, TCAs, SSRIs, some antiemetics)

- Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedicalLectures/

#AKI #Acute #Kidney #Injury #Medications #Drugs #pharmacology #differential #diagnosis