Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s subtle acantholysis on the “normal” skin frozen section, thus partially the IgG looks like it has a granular intercellular deposition.


 -Silvija Gottesman MD

@SGottesmanMD


#Pemphigus #Vulgaris #Pathology #Microscopy #Dermatology #Clinical