Secondary Syphilis Rash
Secondary syphilis is the ...

Secondary Syphilis Rash

Secondary syphilis is the most contagious of all the stages of this disease, and is characterized by a systemic spread of the Treponema pallidum bacterial spirochetes. Skin rash and malaise commonly characterize the secondary stage. The signs and symptoms of secondary syphilis will resolve with or without treatment, but without treatment, the infection will progress to the latent and late stages of disease.

 ▪ “Rash” (75%-90% of patients)

 ▪ Malaise, fever (50-80%)

 ▪ Mucous patches on oral cavity and genital areas (5-30%)

 ▪ Moist, heaped, wart-like lesions—Condyloma lata—on genital, anal or oral areas (5-25)

 ▪ Hair loss (10-15%)

 ▪ Neurosyphilis (<2%)

Characteristic rash

The characteristic rash of secondary syphilis may appear as rough, red, or reddish brown spots both on the palms of the hands and the bottoms of the feet. However, rashes with a different appearance may occur on other parts of the body, sometimes resembling rashes caused by other diseases. Sometimes rashes associated with secondary syphilis are so faint that they are not noticed.

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Contributed by

Dr. Gerald Diaz
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: | Twitter:

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