Nail Disorders secondary to Systemic Diseases

Nail Fold Abnormality

 • SLE

 • Scleroderma

 • Dermatomyositis

Koilonychia - Spoon-shaped

 • Iron deficiency anemia

Onycholysis - Plate Separating from Bed

 • Hyperthyroidism

Beau's Lines - Horizontal Grooves

 • Any systemic disease severe enough to transiently halt nail growth (e.g.. shock, malnutrition)

Blue Discoloration

 • Medications

 • Wilson's disease

 • Silver poisoning

 • Cyanosis

Red Discoloration - Splinter hemorrhages (dark red, thin lines, usually painful

 • Bacterial endocarditis

 • Trauma

Terry's Nails - Proximal 90% (White discoloration)

 • Liver cirrhosis

 • Congestive heart failure

 • Diabetes Mellitus

Half-and-Half Nails (50%)  (White discoloration)

 • Chronic renal failure

 • Uremia

Muehrcke's Lines - Transverse lines  (White discoloration)

 • Nephrotic syndrome



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